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| Seeing Green
| | | Hian Kee Lee from the National University of Singapore is at the cutting edge of developing an array of simple and "environmentally friendly" sample preparation techniques for environmental analysis, writes Alasdair Matheson
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| Effects of Sample-dissolving Solvent and Sample Ionic Strength in Routine CE Operation
| | | By
Kevin Altria
| | | The ionic strength of a sample and the solvent used to dissolve it play a pivotal role in routine capillary electrophoresis (CE). The effects of these parameters can be very pronounced, ranging from improved separation and sensitivity to loss of resolution, shifting migration times, and even to equipment breakdown. CE practitioners should pay special attention to the sample-dissolving solvent and the ionic strength of the sample during method development, validation and routine operation.
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| Immunosorbents for Selective Sample Preparation of Complex Mixtures
| | | By
Ronald E. Majors
| | | Selective sample preparation techniques are particularly attractive for the analysis of trace amounts of small molecules in complex matrices. In this article, Ron Majors covers the field of immunoextraction, a technique that employs immobilized antibodies to selectively capture specific analytes using molecular recognition via antibody–antigen interactions. Recently, the introduction of commercial products for specific high-volume environmental and food safety applications should spur further applications of this technique.
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