Application Notes

Preparative Separation of Polar Compounds using Atlantis T3 OBD Technology

Automated Off-Line Two-Dimensional LC–MS–MS of Complex Proteomic Samples with the UltiMate 3000 System

Chemical Characterization of Calvados (Apple Brandy) Young Spirits: Separation of Polar and Non-Polar Volatile Compounds

Improving Sample Introduction in Arson Investigation Through Sample Re-Collection in Automated Thermal Desorption

Use of an Efficient LC Method Development Approach in the Analysis of Terfenadine, Fexofenadine and Azaclonol

A "Solid" Alternative for Analysing Oxygenated Hydrocarbons — Agilent's New Capillary GC PLOT Column

Rapid Analysis of Ginseng Using Accelerated Solvent Extraction and HPLC

Automated High-Throughput Formula Determination and Confirmation with "sub-ppm" Confidence

Determination of Melamine and Cyanuric Acid by LC–MS Using an Acclaim Mixed-Mode WAX-1 Column and MSQ Plus MS Detection

MORE ARTICLES

Application Notes - Biological

Efficient extraction of basic drugs from biological matricesusing a polymeric cationic mixed-mode sorbent - strata? X-C

Determination of Trace Concentrations of Cations and Amines in Hydrogen Peroxide

Principle Component Analysis of Urine Samples Based on ESI-TOF-MS Data

MORE ARTICLES

Application Notes - Environmental

Acclaim Explosives Columns - Complete Solution for U.S. EPA Method 8330

Environmental Volatile Organic Compounds (VOCs) by Headspace Trap with GC-MS

Optimizing PAH LC/PDA Separation Using Fully-Automated Spectral Processing

Analysis of Polybrominated Diphenyl Ethers Using the Clarus 500 GC-MS

MORE ARTICLES

Application Notes - Food and Beverage

Analysis of Cis and Trans Fatty Acid Methyl Esters from Margarine by Capillary GC

Rapid Extraction and Determination of Arsenicals in Fish Tissue and Carrots Using ASE

Determination of Biogenic Amines in Spoiled Cheese by Ion Chromatography

SPE Sample Preparation for UPLC-MS Determination of Enrofloxacin (Baytril) in Chicken

Eliminating Carbonate from Cola Samples Prior to Injection

MORE ARTICLES

Application Notes - General

UV Transparent Fluoropolymer Coated Capillary Tubing

Enhanced Retention of Polar Analytes Utilizing Novel 1.7 µm UPLC Particles for HIC

Automated Sample Re-Collection for Thermal Desorption Sampling

MORE ARTICLES

Biological and Clinical Assays

Analysis of Volatile Bacterial Metabolites by Gas Chromatography–Mass Spectrometry

Profiles in Practice Series: A Revolution in Clinical Chemistry

MORE ARTICLES

Capillary Electrophoresis

Analysis of Combinatorial Natural Products by HPLC and CE

The Application of Multiplexed Microemulsion Electrokinetic Chromatography for the Rapid Determination of log Pow Values for Neutral and Basic Compounds

MORE ARTICLES

Chiral Separations

Preparative Chiral SFC as a Green Technology for Rapid Access to Enantiopurity in Pharmaceutical Process Research

MORE ARTICLES

Chromatographic Theory

Planar Chromatography Versus Column Chromatography: A Performance Comparison

Characterization of Hyaluronic Acid with On-Line Differential Viscometry, Multiangle Light Scattering, and Differential Refractometry

The Retention Gap Effect

Anatomy of a Peak

Broad Peaks

Solid-Phase Microextraction

Extracolumn Effects

Are You Getting the Most Out of Your HPLC Column?

The Use of Micrometer-Sized Particles in Ultrahigh Pressure Liquid Chromatography

MORE ARTICLES

Chromatography Market Profile

Market Profile: Fast Liquid Chromatography

Chromatography Market Profile: Analytical Instrumentation for Security Applications

Chromatography solutions development

Extraction Techniques for Environmental Samples

Flash Chromatography

Pharmaceutical Market Demand for Life Science Instrumentation

Life Science Research

MORE ARTICLES

Column Watch Column

HPLC Columns - Q's and A's

Multidimensional and Comprehensive Liquid Chromatography

Highlights of HPLC 2005

Preparative Chiral SFC as a Green Technology for Rapid Access to Enantiopurity in Pharmaceutical Process Research

Preparative Chiral SFC as a Green Technology for Rapid Access to Enantiopurity in Pharmaceutical Process Research (PDF)

The Role of the Column in Preparative HPLC

Are You Getting the Most Out of Your HPLC Column?

The Use of Micrometer-Sized Particles in Ultrahigh Pressure Liquid Chromatography

The Cleaning and Regeneration of Reversed-Phase HPLC Columns

MORE ARTICLES

Environmental Analysis

Enhanced Retention of Polar Analytes Utilizing Novel 1.7 µm UPLC Particles for Hydrophilic Interaction Chromatography

Enhanced Sample Throughput for Environmental Analysis

In-Tube Solid-Phase Microextraction and On-Line Coupling with High-Resolution GC

Determination of Common Inorganic Anions in Environmental Waters Using a Hydroxide-Selective Column

Analysis of Various Cyanobacterial Toxins by LCMS

GC Analysis of Trihalomethanes in Drinking Water  A Rapid and Direct Quantitative Method

A GCMS Purge-and-Trap Method Comparison Study for MTBE Analysis in Groundwater

Determination of Phthalate Esters by Positive Chemical Ionization MS with Retention-Time Locked GC

MORE ARTICLES

Equipment Design and Modification

Syringes for Gas Chromatography

The Thermal Conductivity Detector

MORE ARTICLES

Equipment Maintenance and Troubleshooting

HPLC Columns - Q's and A's

Check Valve Problems

Communicating with the Baseline

MORE ARTICLES

Featured Articles

Simultaneous Determination of Positive and Negative Counterions Using a Hydrophilic Interaction Chromatography Method

Gradient Performance Problems - A Case Study

Modern Techniques for the Extraction of Solid Materials - An Update

Making a Great Connection

Dwell Volume Revisited

Syringes for Gas Chromatography

How to Retain Polar and Nonpolar Compounds on the Same HPLC Stationary Phase with an Isocratic Mobile Phase

Analysis of Volatile Bacterial Metabolites by Gas Chromatography–Mass Spectrometry

Method Validation and Robustness

MORE ARTICLES

Flash Articles

Approaches to Synthesizing MIPs for SPE

Screening Acid-Base Constants by CE

Facilitated Column Selection in RPLC

Comparing Approaches to Speed Up LC

Membrane-Assisted LLE Trace Analysis

MORE ARTICLES

Food and Beverage Analysis

Determination of Stilbenes in Blueberries

Analysis of Fusarium Toxins Using LC–MS-MS: Application to Various Food and Feed Matrices

Estimation of Triterpenes in Wines, Spirits, and Oak Heartwoods by LCMS

Applications of Chiral LigandExchange Chromatography for the Analysis of D- and L-Lactic Acid Content of Wine and Other Foodstuffs

MORE ARTICLES

GC Connections Column

Making a Great Connection

Syringes for Gas Chromatography

The Thermal Conductivity Detector

How To Buy Gas Calibration Mixes

The Making of a Column

What's in a Method?

Finding a Needle in a Haystack

The Retention Gap Effect

Anatomy of a Peak

MORE ARTICLES

GC-MS

Analysis of Volatile Bacterial Metabolites by Gas Chromatography–Mass Spectrometry

Determination of Stilbenes in Blueberries

MORE ARTICLES

Gas Chromatography

Gas chromatography triumph

Making a Great Connection

The Thermal Conductivity Detector

Enhanced Retention of Polar Analytes Utilizing Novel 1.7 µm UPLC Particles for Hydrophilic Interaction Chromatography

Polybrominated Diphenyl Ether Analysis in Fish Tissue and Other Matrices by GC—ECD

The Retention Gap Effect

In-Tube Solid-Phase Microextraction and On-Line Coupling with High-Resolution GC

Anatomy of a Peak

Solid-Phase Microextraction

MORE ARTICLES

History

Stephen Dal Nogare: The Person Behind the Award

MORE ARTICLES

Hyphenated Techniques

Determination of Phthalate Esters by Positive Chemical Ionization MS with Retention-Time Locked GC

Fast, Efficient Separations in Drug Discovery  LCMS Analysis Using Column Switching and Rapid Gradients

MORE ARTICLES

Industry News

Pittcon Announces 2007 Award Recipients

Science Week to Be Held at Pittcon 2007

Grace Announces New BioFuel Technologies Group

Waters Corporation and Imperial College London Expand Systems Biology Collaboration

Thermo Wins Omega Award for Service Excellence for Second Consecutive Year

Aspectrics and CPAC Enter Strategic Agreement

Thar technologies Expands Reach of Supercritical Fluid Chromatography

California Vineyard Uses High-Tech Chemistry to Choose Optimum Picking Time for Grapes

PerkinElmer Acquires Avalon Instruments, Adding Raman Spectroscopy Capability

MORE ARTICLES

Injection Techniques

Retaining Polar Compounds

Communicating with the Baseline

MORE ARTICLES

LC Detectors

Characterization of Hyaluronic Acid with On-Line Differential Viscometry, Multiangle Light Scattering, and Differential Refractometry

MORE ARTICLES

LC Troubleshooting

The Perfect Method, Part 1: What Is Your Goal?

Variability — How to Control It

Solvent Conservation

Practical Guidelines in the Care and Maintenance of Capillary GC Columns

Method Reproducibility — A Case Study

Questions from India

Experimental Design Approaches in Method Optimization

MORE ARTICLES

LC Troubleshooting Column

Gradient Performance Problems - A Case Study

Dwell Volume Revisited

Check Valve Problems

Broad Peaks