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Stationary Phases for LC

How to Retain Polar and Nonpolar Compounds on the Same HPLC Stationary Phase with an Isocratic Mobile Phase

Jun 1, 2006
By:Joseph J. Pesek, Maria T. Matyska

Separation and retention of both polar and nonpolar compounds by the same stationary phase can be a useful approach for analyses of complex samples with a broad range of chemical properties.

Evaluation of Polar-Embedded and Polar-Endcapped C12-C18 Stationary Phase Vulnerabilities Toward Highly Nucleophilic Compounds: A Case Study

Sep 1, 2005
By:Larry J. Burge, Christina M. Sorgen

Here the authors discuss an ion-pair, gradient HPLC method, developed for cycloserine-related substances using a polar, amide-embedded C18 column. Other polar-embedded and polar-endcapped columns are evaluated in equivalence studies.

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