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Analysis of Fusarium Toxins Using LC–MS-MS: Application to Various Food and Feed Matrices

Sep 1, 2005

A reliable method for the determination of type A- and B-trichothecenes and zearalenone in cereal-based samples is presented.

A High-Volume, High-Throughput LC–MS Therapeutic Drug Monitoring System

Jun 1, 2005

LC-MS monitoring of the drug clozapine is detailed along with a description of the overall system architecture, workflow, and maintenance routines that support a large-scale drug monitoring program.

Elevated Temperature HPLC: Principles and Applications to Small Molecules and Biomolecules

Mar 1, 2005

The use of elevated and high temperatures in high performance liquid chromatography (HPLC) is reviewed, encompassing the range ambient to 250 °C and with examples covering separations of both small molecules and...

The Analysis of Fluorescent Whitening Agents Using Reversed-Phase HPLC and Mass Spectrometry

Sep 1, 2004

This article describes the separation of individual congeners of commonly used fluorescent whitening agents by reversed-phase high performance liquid chromatography and subsequent time-of-flight mass spectrometry analysis. The authors also compare the...

Estimation of Triterpenes in Wines, Spirits, and Oak Heartwoods by LCMS

Mar 1, 2004

Pedunculate Quercus robur L. and sessile Q. petraea Liebl oak heartwoods are used commonly in the aging process of wine and spirits. During maturation, the ethanol content of these beverages

Analysis of Various Cyanobacterial Toxins by LCMS

Nov 1, 2003

Microcystins represent an emerging class of algal toxins of concern to the drinking water industry. Consequently, the World Health Organization, Australia, and Brazil have established guidelines for the amount of...

Fast, Efficient Separations in Drug Discovery  LCMS Analysis Using Column Switching and Rapid Gradients

Mar 1, 2002

Parallel synthetic techniques (1) and parallel biological screening (2) place tremendous time constraints upon analytical chemists to provide results in a rapid fashion. The mass selectivity of liquid chromatographymass...

Communicating with the Baseline

Mar 1, 2002

The baselines observed in liquid chromatography (LC) separations vary widely in appearance. They range from smooth, straight traces to backgrounds that are filled with humps and bumps. However, if these...

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