HPLC Columns - Q's and A's Mar 1, 2006 By: Ronald E. Majors

In this month's "Column Watch," Ron Majors answers HPLC column questions posed by readers and others.

Multidimensional and Comprehensive Liquid Chromatography Oct 1, 2005 By: Ronald E. Majors

Ron Majors discusses advances in multidimensional chromatography and comprehensive multidimensional chromatography. In particular, the bright future of LC X LC, a technique currently in its infancy, is discussed.

Highlights of HPLC 2005 Sep 1, 2005 By: Ronald E. Majors

HPLC 2005 was held in Stockhom, Sweden, June 26-30. In this month's installment of "Column Watch," Ron Majors covers this year's hot topics including proteomics, column technology - especially monoliths - microfluidics, and multidimensional and high-throughput separations.

Preparative Chiral SFC as a Green Technology for Rapid Access to Enantiopurity in Pharmaceutical Process Research Jun 1, 2005 By: Christopher J. Welch, William R. Leonard Jr., Jimmy O. DaSilva, Mirlinda Biba, Jennifer Albaneze-Walker, Derek W. Henderson, Brian Laing, David J. Mathre

This month's installment of "Column Watch" provides an overview of green chemistry considerations for the kilogram-scale preparative chromatographic separation of enantiomers, focusing especially on recent results from the authors' laboratories, illustrating solvent and time savings realized with preparative supercritical fluid chromatography (SFC). They compare optimized high performance liquid chromatography and SFC in terms of energy efficiency and throughput.

Recently, the subject of green chemistry has received considerable attention from academic and industrial researchers alike. While the central tenets of waste reduction, process economy, and elimination of risks and...

In the course of writing this year's Pittcon coverage of high performance liquid chromatography (HPLC) columns (1,2), I observed that large numbers of columns and packing materials designed for preparative...

This months Column Watch discusses low-dispersion columns, describes how to modify high performance liquid chromatography systems to work with the small-volume columns, and provides guidance about obtaining the optimum capabilities from these columns...

During the past 20 years, researchers have investigated several approaches for improving the separation power of standard chromatography columns, which provide 20,000 theoretical plates. Packing conventional 3- and 5-µm...

Reversed-phase chromatography is by far the most widely used technique in high performance liquid chromatography (HPLC) (1). It is popular because it is applicable to most nonpolar analytes and to...