 | Jun 1, 2005
By:Jason Waters, Danielle Leiske
the material characteristics of Hyaluronic acid are explored by combining a MALS instrument, a differential refractometer, and a differential viscometer with SEC and the results reported.
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Sep 1, 2004
By:John V. Hinshaw
A reader sent me the following question by e-mail: As I read the recent article about the anatomy of a peak (1), I had to ask the following...
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Jun 1, 2004
By:John V. Hinshaw
The human sense of shape and pattern recognition can discern subtle nuances among groups of visual cues that no computer system can reproduce faithfully. Yet when it comes to measuring...
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Jun 1, 2004
By:John W. Dolan
Peaks that are too broad can mean that analysts are not using their liquid chromatography (LC) columns very efficiently. Narrow peaks can translate into faster runs, because less time...
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Mar 1, 2004
By:John V. Hinshaw
Gas chromatography (GC) is a highly sensitive and selective separation technique all by itself. Capable of resolving hundreds of components in a short time with part-per-million (ppm, one part in...
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Mar 1, 2004
By:John W. Dolan, Ryan M. Minikis
This month's "LC Troubleshooting" centers on a problem encountered in our laboratory that we initially attributed to extracolumn effects. However, a closer examination of the experimental data reduced our confidence...
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Mar 1, 2004
By:Ronald E. Majors
This months Column Watch discusses low-dispersion columns, describes how to modify high performance liquid chromatography systems to work with the small-volume columns, and provides guidance about obtaining the optimum capabilities from these columns...
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Nov 1, 2003
By:Anton D. Jerkovich, J. Scott Mellors, James W. Jorgenson
During the past 20 years, researchers have investigated several approaches for improving the separation power of standard chromatography columns, which provide 20,000 theoretical plates. Packing conventional 3- and 5-µm...
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