Planar Chromatography Versus Column Chromatography: A Performance Comparison Jun 1, 2005 By: Pawel K. Zarzycki, Kathrin M. Kulhanek, Roger Smith, Malgorzata A. Bartoszuk, Henryk Lamparczyk

The authors explore the hypothesis that in particular cases, conventional planar chromatography can actually provide more effective and robust systems than column chromatography.

Characterization of Hyaluronic Acid with On-Line Differential Viscometry, Multiangle Light Scattering, and Differential Refractometry Jun 1, 2005 By: Jason Waters, Danielle Leiske

the material characteristics of Hyaluronic acid are explored by combining a MALS instrument, a differential refractometer, and a differential viscometer with SEC and the results reported.

A reader sent me the following question by e-mail: As I read the recent article about the anatomy of a peak (1), I had to ask the following...

The human sense of shape and pattern recognition can discern subtle nuances among groups of visual cues that no computer system can reproduce faithfully. Yet when it comes to measuring...

Peaks that are too broad can mean that analysts are not using their liquid chromatography (LC) columns very efficiently. Narrow peaks can translate into faster runs, because less time...

Gas chromatography (GC) is a highly sensitive and selective separation technique all by itself. Capable of resolving hundreds of components in a short time with part-per-million (ppm, one part in...

This month's "LC Troubleshooting" centers on a problem encountered in our laboratory that we initially attributed to extracolumn effects. However, a closer examination of the experimental data reduced our confidence...

This months Column Watch discusses low-dispersion columns, describes how to modify high performance liquid chromatography systems to work with the small-volume columns, and provides guidance about obtaining the optimum capabilities from these columns...

During the past 20 years, researchers have investigated several approaches for improving the separation power of standard chromatography columns, which provide 20,000 theoretical plates. Packing conventional 3- and 5-µm...